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BIOLOGY 537 - IMMUNOLOGY Tentative LECTURE SCHEDULE, FALL, 2001 DR. FRED McCORKLE OFFICE HOURS: Brooks 114 Mon :1-3 PM 774-3348 Tue :1-3 PM or by Appt. DATE TOPIC Aug 28 Introduction, History, Natural Immunity 30 Acquired Immunity, Structure of Immune System Sept 4 Phagocytosis 6 Inflammation
11 Lymphomyeloid Complex 13 Antibodies 18 Clonal Selection 20 Antibody - Antigen Interactions 25 Immunoglobulin Structure
27 Immunoglobulin Classes and Subclasses Oct 2 EXAM Oct 4 Immunogenetics 9 Antigens 11 Complement 16 T - Lymphocytes 18 Immediate Hypersensitivity 23 Cytotoxic Hypersensitivity 25 Immune - Complex and Cell-Mediated Hypersensitivities 30 Transplantation Immunity Nov 1 Tolerance Nov 6 EXAM Nov 8 Immunity to Bacterial Disease 13 Immunity to Viral Disease 15 Immunity to Parasitic Diseases 20 Reproductive Immunity 22 THANKSGIVING HOLIDAY 27 Tumor Immunity
29 Immune Deficiency Disorders Dec 4 Aging and Immunity 6 Autoimmunity 11 FINAL EXAM 8:00 - 9:50 AM Tuesday Textbook: Immunology Janis Kuby
LAB MANUAL: BookStore Laboratory Manual - Immunology Biology 537
GRADING: 2 Hour Exams 40% ( 20% Each ) Final Exam 20% Laboratory Work 10% Laboratory Notebook 20% Term Paper 10% Term Paper due **** NOVEMBER 15, 2001. The term paper will be a synopsis dealing with a specific area of Immunology based upon information from at least 5 original research articles from current scientific journals. A photocopy of the first page of each article will be included with the paper. This paper should be no less than 5 typed pages. Papers turned in late ( up to three days ) will automatically receive a 10% reduction in grade per day. Those over three days late will NOT be accepted. This paper can not have been used for any other course Graduate Students must turn in a 3 Page review of a current research article in Immunology by November 1, 2001 to get credit for this course, include a copy of the article.
CMU provides students with disabilities reasonable accommodation to participate in educational programs, activities or services. Students with disabilities requiring accommodation to participate in class activities or meet course requirements should first register with the office of Student Disability Services (250 Foust Hall, telephone #517-774-3018, TDD #2568), and then contact me as soon as possible. .
Classroom Civility : Each CMU student is encouraged to help create an environment during class that promotes learning, dignity, and mutual respect for everyone. Students who speak at inappropriate times, sleep in class, display inattention, take frequent breaks, interrupt the class by coming to class late, engage in loud or distracting behaviors, use cell phones or pagers in class, use inappropriate language, are verbally abusive, display defiance or disrespect to others, or behave aggressively toward others could be asked to leave the class and subjected to disciplinary action under the Code of Student Rights, Responsibilities and Disciplinary Procedures. Policy on Academic Integrity: In may 2001, the Central Michigan University Academic Senate approved the Policy on Academic Integrity which applies to all university students. Copies are available on the CMU website at and in the Academic Senate Office in room 108 of Bovee University Center. All academic work is expected to be in compliance with this policy.
Library Paper for Immunology The purpose of this assignment is to introduce you to the primary literature of immunology and to encourage critical thinking skills. The library paper is due Nov. 15, 2001. The library paper will be on a topic of your own choosing but must be on a Immunology topic.. T Write a 5-6 page library paper using at least 5 original research articles (12-pt. double-spaced, 1" margins) including a short introduction. Review articles may be used as these synthesis the experiments of others rather than describing original experiments but these review articles will not count as original research articles. Thus, there are no methods and materials or results sections in review articles. Research articles describe original experiments that the authors have done, and usually follow the standard format of Introduction, Materials and Methods, Results, Discussion, References. The exceptions are research articles published in Science or Nature magazines; in these journals, to save space the methods are briefly described in either the figure legends or in footnotes, and the article is not broken up by section subheadings. The main body will address the research of the these papers on your topic. Use V. E. McMillans Writing Papers in the Biological Sciences the Third Edition as a source for style and technique.
Title format: Title.
Introduction: Do not use heading, do restrict to one or two paragraphs. The textbook should not be referenced. Remember to reference all this work as it is not your work. This is true for this whole paper.
Body: Do not use heading, but start a new paragraph with an introductory sentence such as, "In the study by Frye and Edidin (1970), ..." Explain any unusual techniques used; if you don't understand the methods, do some research to find out about them. Address the hypothesis of the experimenters, the specific experiments to test the hypothesis, and the conclusions drawn. What controls were done? Were you convinced by the results? How strong was their experimental evidence? Did the authors over-interpret their data in the Discussion section?
References: Use a heading for this section only. Alphabetize by first author. Provide complete author list, date, title, journal, volume, and pages.
Citation style: Use (Hertzler, 1998) for one author, (Hertzler and McCorkle, 1998) for two authors, and (Hertzler et al., 1998) for multiple authors within the text. Use (reviewed by Hertzler, 1998) to reference your review in the first paragraph. Use a citation after the first sentence of your research paper discussion, and again whenever a major finding or conclusion is made. Do not cite page numbers. Papers with missing citations will receive a Zero.
Spelling and Grammar: Use but don't rely on the spell-checker on your computer. Always proofread. Points will be lost for sloppy proof reading.
Plagiarism: Do not use quotation marks to cite passages. Put things in your own words. You may think the authors expressed their sentence in the best possible way, but you must rephrase it, and correctly attribute it. I will check the reference if in doubt, and plagiarized papers will receive a Zero with the possibility of further action through the Office of Student Life. If you are unsure of what constitutes plagiarism, consult the handbook PLAGIARISM: A BRIEF OVERVIEW.
Library Use of articles: You must either use references in the library or make a photocopy. Ripping out research articles from journals in the library is a scholarly crime as well as theft and destruction of state property, and will be addressed accordingly.
Library Paper Grading: The paper will be worth 100 points. Papers received late will receive a 5 point per day reduction, starting after the class period on the day due and will not be accepted after three days. Do not use personal pronouns in your paper ( they, I , He or She). You will lost one point each time you use these. This paper can not have been used in any other course at CMU or other college or university. |