Mary M. J. Tecklenburg

Associate Professor

Department of Chemistry

Central Michigan University

 

I.     Personal

 

Office: Dow Building, Room 353                                              Phone: 989‑774‑3078

e-mail: mary.tecklenburg@cmich.edu                                       FAX: 989-774-3883

 

II.    Education

 

Ph.D. Physical Chemistry, Texas A&M University, January 1989, Dissertation Title: Vibrational Spectroscopy and Conformational Analyses of Small Ring Molecules.

M.S. Analytical Chemistry, Indiana University ‑ Purdue University at Indianapolis, August 1983.

Thesis Title:  Electrostatic Contributions in Aqueous Exclusion Chromatography.

B.S. Chemistry, St. Louis University, May 1982. Magna Cum Laude

 

III.   Employment History

 

Central Michigan University, Associate Professor                                              1998-present

University of Michigan, Visiting Professor                                                         2000-2001

Central Michigan University, Assistant Professor                                                       1991‑1998

Michigan State University, National Institutes of Health Postdoctoral

Fellow                                                                                                     1989‑1991

Texas A&M University, National Science Foundation Research Assistant                   1984‑1988

Texas A&M University, Teaching Assistant                                                       1983‑1986

Pathfinder Laboratories, Maryland Heights, MO, Laboratory Assistant               1981‑1982

 

IV.   Teaching Experience

 

CHM 131 Introduction to Chemistry I

CHM 132 Introduction to Chemistry II

CHM 127 Introductory Chemistry Lab

CHM 351 Physical Chemistry I

CHM 352 Physical Chemistry II

CHM 357 Physical Chemistry Lab I

CHM 358 Physical Chemistry Lab II

CHM 511 Advanced Analytical Chemistry

CHM 583 Seminar

CHM 611 IR/Raman Spectrometry

CHM 651 Computational Chemistry

CHM 679 Theory of Spectroscopy

            CHM 683 Thermodynamics

 

V.    Creative and Scholarly Activity

 

        A. Publications, Peer Reviewed

1.      Ayorinde Awonusi, Michael D. Morris, Mary M. J. Tecklenburg, “Carbonate Assignment and Calibration in the Raman Spectrum of Apatite” Calcified Tissue International, 2007, in press.

2.      E. E. Wilson, Ayorinde Awonusi, M. D. Morris, D. H. Kohn, M. M. J. Tecklenburg, L. Beck,  “Three Structural Roles of Water in Bone Observed by Solid-State NMR” Biophysical Journal, 2006, 90, 3722-3731.

3.      O. de Carmejane, M. D. Morris, M. K. Davis, L. Stixrude, M. Tecklenburg, R. M. Rajachar and D. H. Kohn, “Bone Chemical Structure Response to Mechanical Stress Studied by High Pressure Raman Spectroscopy,” Calcified Tissue International, 2005, 76, 207-213.

4.      Erin Wilson, Ayorinde Awonusi, Michael Morris, David Kohn, Mary Tecklenburg, Larry Beck, “Highly Ordered Interstitial Water Observed in Bone by Nuclear Magnetic Resonance,” Journal of Bone and Mineral Research, 2005, 20, 625-634.

5.      Mary M. J. Tecklenburg, Elisabeth Larsen, Bogdan Lita, Didarul I. Qadir, “Effect of Copper on the Local Structure of GeSe2Cux Probed by Raman Spectroscopy,” Journal of Non-Crystalline Solids, 2003, 328, 40-47.

6.      Mary M. J.  Tecklenburg, Derek Kosnak, Atul Bhatnagar and Dillip Mohanty, "Vibrational Characterization of Azobenzenes, Azoxybenzenes and Azoaromatic and Azoxyaromatic Polyethers," Journal of Raman Spectroscopy, 1997, 28, 755-763.

7.      J. P. Hosler, J. P. Shapleigh, M. M. J. Tecklenburg, J. W. Thomas, Y. Kim, M. Espe, J. Fetter, G. T. Babcock, J. O. Alben, R. B. Gennis, and S. Ferguson‑Miller, "A Loop Between Trans‑Membrane Helices IX and X of Subunit I of Cytochrome c  Oxidase:  The Heme a‑Heme a3‑CuB Center," Biochemistry, 1994, 33, 1194‑1201.

8.      L. A. Leal, D. G. Lister, J. L. Alonso, M. M. J. Tecklenburg, J. R. Villarreal, and J. Laane, "Microwave Spectrum and Conformation of 5,6‑Dihydro‑2H‑thiopyran," Journal of the Chemical Society Faraday Transactions, 1994, 90, 2849‑2856.

9.      J. P. Hosler, S. Ferguson‑Miller, M. W. Calhoun, J. W. Thomas, J. Hill, L. Lemieux, J. Ma, C. Georgiou, J. Fetter, J. Shapleigh, M. M. J. Tecklenburg, G. T. Babcock and R. B. Gennis, "Insight into the Active‑Site Structure and Function of Cytochrome Oxidases by Analysis of Site‑Directed Mutants of Bacterial Cytochrome aa3  and Cytochrome bo, " Journal of Bioenergetics and Biomembranes, 1993, 25, 121‑136.

10.   M. W. Calhoun, J. W. Thomas, J. J. Hill, J. P. Hosler, J. P. Shapleigh, M. M. J. Tecklenburg, S. Ferguson‑Miller, G. T. Babcock, J. O. Alben, and R. B. Gennis, "Identity of the Axial Ligand of the High‑Spin Heme in Cytochrome Oxidase: Spectroscopic Characterization of Mutants in the bo‑type Oxidase of Escherichia coli  and the aa3‑type Oxidase of Rhodobacter sphaeroides," Biochemistry,  1993, 32,  10905‑10911.

11.   J. P. Shapleigh, J. P. Hosler, M. M. J. Tecklenburg, Y. Kim, G. T. Babcock, R. B. Gennis and S. Ferguson‑Miller, "Definition of the Catalytic Site of Cytochrome c  Oxidase: Specific Ligands of Heme a  and the Heme a3‑CuB Center," Proceedings of the National Academy of Science USA, 1992, 89, 4786‑4790.

12.   M. Lauraeus, M. Wikström, C. Varotsis, M. M. J. Tecklenburg, and G. T. Babcock, "Optical and Resonance Raman Spectroscopy of the Heme Groups of the Quinol‑Oxidizing Cytochrome aa3 of Bacillus subtilis,"  Biochemistry, 1992, 31, 10054‑10060.

13.   J. P. Hosler, J. Fetter, M. M. J. Tecklenburg, M. Espe, C. Lerma and S. Ferguson‑Miller, "Cytochrome aa3 of Rhodobacter Sphaeroides  as a Model for Mitochondrial Cytochrome c Oxidase:  Purification, Kinetics, Proton Pumping and Spectral Analysis," Journal of Biological Chemistry,  1992, 267, 24264‑24272.

14.   Mary M. J . Tecklenburg and Jaan Laane, "Kinetic Energy Functions of the Ring‑Bending and Ring‑Twisting Vibrations of Asymmetrically Substituted Six‑Membered Rings," Journal of Molecular Spectroscopy, 1989, 137, 65‑81.

15.   Mary M. J. Tecklenburg, John R. Villarreal, and Jaan Laane, "Vibrational Spectra and Potential Energy Surface for the Ring‑Bending and Ring‑Twisting of 5,6‑Dihydro‑2H‑thiopyran," Journal of Chemical Physics, 1989, 91, 2771‑2775.

16.   Mary M. J. Tecklenburg and Jaan Laane, "Vibrational Potential Energy Surfaces of 3,4‑Dihydro‑2H‑pyran, 3,6‑Dihydro‑2H‑pyran, 2,3‑Dihydro‑1,4‑dioxin and 4H‑1,3‑Dioxin," Journal of  the American Chemical Society, 1989, 111, 6920‑6926.

17.   Paul L. Dubin and Mary M. Tecklenburg, "Size Exclusion Chromatography of Strong Polyelectrolytes," Analytical Chemistry, 1985, 57, 275.

        B.          Publications, Conference Proceedings

1.      M. M. J. Tecklenburg, A. Awonusi, S. Dennis, M. C. Sirbescu, “Ion-substituted Apatites: Standards for Raman Analysis of Bone” Geochimica et Cosmochimica Acta, 2005, 69(10), A73.

2.      Mary M. J. Tecklenburg, Ira Miller, Elisabeth Larsen, Lori Bushert, Bogdan Lita, Didarul Islam, “Probing the Local Structure of Glassy GeSe2Cux: Raman Intensity Variation with Composition and Excitation Frequency,” Proceedings of the Seventeenth International Conference on Raman Spectroscopy, S. Zhang and B. Zhu, Eds., Wiley, 2000 pp. 574-575.

3.      M. M. J. Tecklenburg, J. P. Hosler, J. P. Shapleigh, Y. Kim, R. B. Gennis, S. Ferguson-Miller, and G. T. Babcock, “Resonance Raman Spectroscopy of Cytochome c Oxidase: Identification of the Specific Ligands to Heme a and the Heme a3-CuB Center,” Procedings of the Thirteenth International Conference on Raman Spectroscopy, W. Keifer et. al., Ed., Wiley, 1992, pp. 138-139.

 

C. Publications, Other

1.      K. Brandstadt, M. McIvor, D. Takehara, J. Hand, M. Kumar, M. Bennett, M. Tecklenburg and T. Lane, “Rapid Detection of Organosilicon Molecules in Aqueous Environments by Raman Spectroscopy”, Dow Corning Corporation, Technical Report, 2003-I0000-53281, December 1, 2003.

 

D. Presentations

1.      Mary M. J. Tecklenburg, Ayorinde Awonusi “Carbonate Assignment and Calibration in the Raman Spectra of Apatite and Bone” International Conference on Raman Spectroscopy, Yokohama, Japan, August 21 –25, 2006.

2.      Mary M. J. Tecklenburg, Paul Wrzesinski, Martin Bennett, Lindsey Suhr, and Kurt F. Brandstadt “In Situ Detection of Methoxysilane Hydrolysis Intermediates in a Biomatrix by Raman Spectroscopy” American Chemical Society Central Regional Meeting and 39th Silicon Symposium, Frankenmuth, MI, May 16-20, 2006.

3.      Mary M. J. Tecklenburg, Ayorinde Awonusi and ShaRhonda Dennis “Development of Apatite Standards for Spectroscopic Analysis of Bone” Federation of Analytical Chemistry and Spectroscopy Societies, Quebec, Canada, October 2005.

4.      Mary M. J. Tecklenburg, “Solving Problems in Molecular Structure by Raman Spectroscopy” Paul Dubin Symposium, Indiana Univ.-Purdue Univ.-Indianapolis, July 27, 2005.

5.      M. M. J. Tecklenburg, A. Awonusi,  S.  Dennis, M. C. Sirbescu, “Ion-substituted Apatites: Standards for Raman Analysis of Bone,” Goldschmidt Conference, Moscow, ID May, 2005.

6.      Mary Tecklenburg, Martin Bennett and Kurt Bradstadt, “Rapid Detection of Methylmethoxysilane in a Biomatrix by Raman Spectroscopy,” PittCon, Orlando, FL, March, 2005.

7.      Mary M. J. Tecklenburg, Ayorinde Awonusi, ShaRhonda Dennis, “Raman Spectra of Carbonated Apatites: Effect of Biologically Relevant Ion Substitution” Federation of Analytical Chemistry and Spectroscopy Societies, Portland, OR October 2004.

8.      Mary Tecklenburg, Adam Perala, Amy Marcotte, and Robert Buckland, “Modeling Bone Raman Spectra with Substituted Hydroxyapatite,” Federation of Analytical Chemistry and Spectroscopy Societies, Ft. Lauderdale, FL, October 2003.

9.      Mary M. J. Tecklenburg, Robert Buckland, Amy Marcotte, and Adam Perala, “Studying the Chemical Structure of Bone Through the Raman Spectra of Model Materials,” 59th ACS Midland Section Scientific Meeting, Midland, MI, October 2003.

10.   Mary Tecklenburg, “Raman Spectra of Model Bone: Substituted Hydroxyapatite,” CMU chemistry department seminar, February 24, 2003.

11.   Mary M. J. Tecklenburg, Robert Buckland, Amy Marcotte, and Adam Perala, “Raman Spectra of Model Bone: Substituted Hydroxyapatites” Federation of Analytical Chemistry and Spectroscopy Societies, Providence, RI, October 2002.

12.   Mary M. J. Tecklenburg, Robert Buckland, and Amy Schwerin, “Interpreting the Raman Spectra of Bone Tissue: Vibrations of Model Apatites by Raman Spectroscopy and DFT Calculations,” Federation of Analytical Chemistry and Spectroscopy Societies, Detroit, MI, October 2001.

13.   Mary M. J. Tecklenburg and Koblar A. Jackson, “Interpreting the Raman Spectra of Bone Tissue with DFT calculations on Model Hydroxyapatites” Symposium to Honor Gerald T. Babcock, Michigan State University, E. Lansing, MI, June 1-2, 2001.

14.   Mary M. J. Tecklenburg, Lori Bushert, Ira Miller, Elisabeth Larsen, Bogdan Lita, Didarul Islam, “Raman Intensity Variation in Glassy GeSe2Cux” 55th ACS Fall Scientific Meeting, Midland, MI, November 2000.

15.   Mary M. J. Tecklenburg, Ira Miller, Elisabeth Larsen, Lori Bushert, Bogdan Lita, Didarul Islam, “Probing the Local Structure of Glassy GeSe2Cux: Raman Intensity Variation with Composition and Excitation Frequency” International Conference on Raman Spectroscopy, Beijing, China, August 21 –25, 2000.

16.   Mary M. J. Tecklenburg and Leela Rakesh, “Computational Chemical Modeling Throughout the Curriculum” Biennial Conference on Chemical Education, Ann Arbor, MI, July 31 – August 3 2000.

17.   Mary M. J. Tecklenburg, Elisabeth Larsen, John Black, Bogdan Lita, and Didarul Islam “Raman Spectroscopic Analysis of the Structure of Metal Alloys of Glassy GeSe2,” 54th ACS Fall Scientific Meeting, Saginaw, MI, October 1998.

18.   Mary M. J. Tecklenburg, Elisabeth Larsen, John Black, Bogdan Lita, and Didarul Islam “Raman Spectroscopic Analysis of the Structure of Glassy GeSe2Cux and GeSe2-yTeyMx (M = Zn, Cd, Cu)”, American Chemical Society National Meeting, Boston, MA, August 23 – 27 1998.

19.   Mary M. J. Tecklenburg, Elisabeth Larsen, Bogdan Lita, and Didarul Islam, “Structural Analysis of Glassy Ge1-xMxSe2-yTey (M = Zn, Cd, or Cu) by Raman Spectroscopy” 53rd ACS Fall Scientific Meeting, Mt. Pleasant, MI, November 1997.

20.   Mary M. J. Tecklenburg, Derek J. Kosnak, Atul Bhatnagar, and Dillip K. Mohanty “Raman and Infrared Spectral Characterization of Azoaromatic and Azoxyaromatic Polyethers” American Chemical Society, 20th Central Regional Meeting, Midland, MI May 1997.

21.   Mary M. J. Tecklenburg, "Far‑Infrared Spectroscopy and Conformations of Cyclohexenes," Analytical Sciences Department, Dow Chemical Company, Midland, MI, November 17, 1993.

22.   Mary M. J. Tecklenburg, "Resonance Raman Spectroscopy as a Means to Determine the Structure of Cytochrome c Oxidase," Department of Chemistry, Alma College, Alma, MI, February 23, 1993.

23.   Mary M. J. Tecklenburg, "Conformational Potential Energy Surfaces of Cyclohexenes from Far‑Infrared Spectroscopy," Department of Physics, Central Michigan University, February 4, 1993.

24.   M. M. J. Tecklenburg, C. Varotsis, M. Lauraeus, M. Wikström, and G. T. Babcock, "Resonance Raman Spectroscopy of an Enzyme with a Heme Active Site:  The Cytochrome aa3 Quinol Oxidase of Bacillus subtilis," Fall Scientific Meeting of the American Chemical Society, Midland, MI, November 9, 1992.

25.   M. M. J. Tecklenburg, J. P. Hosler, J. P. Shapleigh, Y. Kim, R. B. Gennis, S. Ferguson‑Miller, and G. T. Babcock, "Resonance Raman Spectroscopy of Cytochrome c Oxidase:  Identification of the Specific Ligands to Heme a and the Heme a3‑CuB Center" International Conference on Raman Spectroscopy, Würzburg, Germany, 1992.

26.   M. M. J. Tecklenburg, C. Varotsis, M. Lauraeus, M. Wikström, and G. T. Babcock, "Resonance Raman Spectroscopy of Bacillus subtilis: The Heme Groups of the Cytochrome aa3 Quinol Oxidase," Symposium on Raman Spectroscopy on Biological Systems, Bremen, Germany, 1992.

27.   M. M. J. Tecklenburg, H. Sung, J. R. Villarreal, and J. Laane, "Vibrational Spectra and Conformational Analysis of Bicyclo[3.2.0]hept‑1(5)‑ene and Silacyclohex‑2‑ene," NATO Advanced Research Workshop on Structures and Conformations of Non‑Rigid Molecules, Günzburg and Ulm, Germany, 1992.

28.   Mary M. J. Tecklenburg, "Spectroscopic Characterization of Heme Proteins and Model Oxygen Carriers," Chemistry Department Seminar, Indiana Univ.‑Purdue Univ. at Indianapolis, November 13, 1991.

29.   J. P. Hosler, M. M. J. Tecklenburg, M. Atamian, A. Revzin, S. Ferguson‑Miller and G. T. Babcock, "Cytochrome c Oxidase (aa3‑Type) of Rhodobacter sphaeroides is Similar to the Mitochondrial Enzyme but Contains a Unique Local Environment for Cytochrome a," Biophysical Society National Meeting, San Francisco, CA, 1991.

30.   J. C. de Paula, W. Pfeifer, R. Ingle, J. A. Centeno, M. M. J. Tecklenburg, S. Ferguson‑Miller and G. T. Babcock, "The Heme a Site of Plant Cytochrome c Oxidases," Gordon Research Conference on Bioenergetics, Plymouth, NH, 1989.

31.   Mary Tecklenburg and Jaan Laane, "Low‑Frequency Vibrational Spectra and Conformational Analysis of Cyclohexene‑Like Molecules", Federation of Analytical Chemistry and Spectroscopy Societies Annual Meeting, Detroit, Michigan, 1987.

32.   M. M. Tecklenburg and J. Laane, "A Conformational Study of the Bending and Twisting Vibrations of Cyclohexene‑Like Molecules", American Chemical Society National Meeting, Denver, Colorado, 1987.

33.   M. M. Tecklenburg, J. R. Villarreal, and J. Laane, "Far‑Infrared Spectrum and Ring‑Puckering Vibration of Bicyclo[3.2.0]hept‑1(5)‑ene," 40th Symposium on Molecular Spectroscopy, Columbus, Ohio, 1985.

 

        E. Student Presentations

1.      Ayorinde Awonusi, ShaRhonda Dennis, and Mary Tecklenburg, “Calibration of Phosphate and Carbonate in Raman Spectra of B-Carbonated Hydroxyapatites and Bone,” 61st ACS Midland Section Scientific Meeting, Midland, MI, October 2005.

2.      Ayorinde Awonusi, ShaRhonda Dennis, and Mary Tecklenburg, “Development of Standards for Raman Analysis of Bone Mineral,” PittCon, Orlando, FL, March, 2005.

3.      Ayorinde Awonusi and Mary M. J Tecklenburg, “Raman Calibration of Phosphate and Carbonate Composition of Bone Mineral” 60th ACS Midland Section Scientific Meeting, Midland, MI, October 2004.

4.      ShaRhonda Dennis and Mary M. J Tecklenburg, “Study and Analysis of Carbonated Apatite, a Model Material for Bone,” 60th ACS Midland Section Scientific Meeting, Midland, MI, October 2004.

5.      Martin Bennett and Mary Tecklenburg, “Monitoring the Hydrolysis of Methylmethoxysilanes in an Aqueous Environment by Raman Spectroscopy,” Federation of Analytical Chemistry and Spectroscopy Societies, Ft. Lauderdale, FL, October 2003.

6.      Martin Bennett, Kurt Brandstadt and Mary Tecklenburg, “Methylmethoxysilane Hydrolysis by Raman Spectroscopy,” 59th ACS Midland Section Scientific Meeting, Midland, MI, October 2003.

7.      Martin Bennett, Kurt Brandstadt and Mary Tecklenburg, “Monitoring the Hydrolysis of Methylmethoxysilanes in Aqueous Environments by Raman Spectroscopy,” Materials Meeting, CMU, May 21, 2003.

8.      Adam Perala and Mary Tecklenburg, “Effect of Chloride Ion on the Raman Spectrum of Hydroxyapatite, a Bone Model,” 58th ACS Midland Section Scientific Meeting, Midland, MI, October 2002.

9.      Amy Marcotte, Robert Buckland and Mary Tecklenburg, “The Effect of Carbonate and Magnesium on the Raman Spectra of Model Bone,” 58th ACS Midland Section Scientific Meeting, Midland, MI, October 2002.

10.   Jennifer E. Silva and Mary M. J. Tecklenburg, “A Study of the Heme a Protein Interaction in Cytochrome c Oxidase by Resonance Raman Spectroscopy,” 53rd ACS Fall Scientific Meeting, Mt. Pleasant, MI, November 1997.

11.   Derek Kosnak and Mary M. J. Tecklenburg "Determination of the Structure of Chalcogenide Glasses Using Raman Spectroscopy," Pittsburgh Conference, Chicago, IL, March 1996.

12.   Marjorie Crouse and Mary M. J. Tecklenburg, "Resonance Raman Study of Hemes of Cytochrome c Oxidase, Myoglobin, and Hemoglobin," Great Lakes College Chemistry Conference, East Lansing, MI, March 16, 1996.

13.   Derek Kosnak and Mary M. J. Tecklenburg "Raman Spectra of Chalcogenide Glasses:  Structural Determination" 51st Midland Meeting of the American Chemical Society, University Center, MI, November 1995.

14.   Jeffrey Feneley, Wei Zhou, and Mary M. J. Tecklenburg, "Analysis of Raman Spectra of Chalcogenide Glasses," Great Lakes College Chemistry Conference, East Lansing, MI, March 1995.

15.   Kevin M. Jacobs and Mary M. J. Tecklenburg, "Low Frequency Raman Study of Heme Containing Enzymes," Great Lakes College Chemistry Conference, East Lansing, MI, March 1995.

16.   James R. Kennis and Mary M. J. Tecklenburg, "Resonance Raman Spectra of Porphyrin Models of Cytochrome c Oxidase," Great Lakes College Chemistry Conference, East Lansing, MI, March 1995.

17.   Douglas McLemore, "Theoretical Approximations of the Auger Transitions in Compounds Containing Atoms from the First Three Rows of the Periodic Table," Great Lakes College Chemistry Conference, East Lansing, MI, March 1995.

18.   D. Islam, W. Zhou, M. M. Tecklenburg, and K. A. Jackson, "Optical and Structural Studies of Glassy Ge1‑xCuxSe2," American Physical Soceity Meeting, San Jose, CA, March 21, 1995 and CMU Faculty Creativity Day, Mt. Pleasant, MI, March 22, 1995.

19.   Brad Schneider, Wei Zhou, Didarul Islam and Mary M. J. Tecklenburg, "Raman Spectra of Chalcogenide Glasses," the 50th ACS Fall Scientific Meeting, Midland, MI, Nov. 5, 1994.

20.   Brad Schneider, Wei Zhou, Didarul Islam and Mary M. J. Tecklenburg, "Local Structure of GeSe2 Glasses from Raman Spectra," Great Lakes College Chemistry Conference, East Lansing, MI, April 9, 1994.

21.   Hong Sung, Matthew T. Smith, and Mary M. J. Tecklenburg, "Development of a Raman Spectrometer for Analysis of Materials," Fall Scientific Meeting of the American Chemical Society, Midland, MI, October 23, 1993.

22.   Angela M. Schroeder, Mary M. J. Tecklenburg, and Wendell L. Dilling, "Theoretical Calculations on Bishomocubyl Systems," Fall Scientific Meeting of the American Chemical Society, Midland, MI, October 23, 1993.

 

 

VI.   Grants and Contracts

 

        A. External Grants and Contracts

1.      National Science Foundation, “FRG: Bioceramic Surface Site Structure and Solution Chemistry Controls on Hydroxylapatite Nucleation Mechanisms and Cellular Activity,” (subcontract to Mary Tecklenburg at CMU, $75,637, 3 years, PIs: Nita Sahai and William Murphy, University of Wisconsin), submitted November 2006.  A study of the growth of bone-like material on silicate surfaces. Pending

2.      National Institutes of Health, “Spectroscopy of Protein Mediation of Bone Mineralization,” (subcontract to Mary Tecklenburg and Marco Fornari at CMU, $203,198, 4 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), submitted October 2006. A study of a model system for bone mineralization; the transformation of octacalcium phosphate to apatite. Not Funded.

3.      National Institutes of Health, “Spectroscopy of Protein Mediation of Bone Mineralization,” (subcontract to Mary Tecklenburg and Marco Fornari at CMU, $225,984, 4 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), submitted February 2006. Not Funded. 

4.      National Institutes of Health, “Raman Imaging of Early Mineralization of Bone Tissue,” (subcontract to CMU, $203,198, 4 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), December 2002.  Interpretation of the Raman spectra of bone through chemical and computational models. Funded.

5.      Dow Corning Corporation, “High Throughput Analytical Assay,” $29,996, May 2002, 1 year, funded.  A feasibility study for the use of Raman spectroscopy for fast screening of organosilicones in biochemical matrices. Funded.

6.      National Institutes of Health, “Raman Imaging of Early Mineralization of Bone Tissue,” revision (subcontract to CMU, $219,574, 4 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), submitted, June 2001. Not Funded.

7.      National Institutes of Health, “Raman Imaging of Early Mineralization of Bone Tissue,” (subcontract to CMU, $175,873, 3 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), submitted, October 2000. Not Funded.

8.      National Science Foundation, “Raman Imaging Studies of Bone Tissue Mineralization,” (subcontract to CMU, $161,280, 3 years, PIs: Michael Morris and Michael Ignelzi, University of Michigan), submitted, July 2000. Not Funded.

9.      National Science Foundation, "Computational Chemical Modeling Throughout the Science Curriculum," (co-investigator: Leela Rakesh) $69,891, September 1996, 2 years.  Description: Computers and molecular modeling software were purchased for use in introductory and advanced chemistry, math, and physics courses. Funded.

10.   Research Corporation Cottrell Science Award, "Investigation of the Heme Conformation in Cytochrome c Oxidase", $29,288, May 1993,  2 years.  The Raman spectra of cytochrome c oxidase will be compared with that of other heme containing proteins and free heme to identify the vibrations associated with the low frequency modes in the spectra. Funded.

11.   AutoDesk, "A Computational Chemistry Laboratory Using HyperChem", $3,500, March 1993, 1 year.  A physical chemistry laboratory exercise was developed to introduce students to molecular modeling using the HyperChem software. Funded.

12.   Faculty Research and Creative Endeavors Award, Central Michigan University, "The Heme Structure in Cytochrome c Oxidase using Resonance Raman Spectroscopy", $4,125, March 1992, 1 year.  Resonance Raman spectra of several heme containing proteins and synthetic hemes were compared with that of cytochrome c oxidase. Funded.

13.   Dow Chemical Company, Analytical Sciences Grant, "Raman Spectroscopy of Materials at Central Michigan University", $8,000, July 1992, 1 year. A Raman spectrometer was built, computer interfaced, and used to study a broad range of materials. Funded.

        B. Internal Grants

1.      CMU 2010, “The Advanced Materials Research Initiative:  Exploiting Synergy to Attain National Prominence in Materials Research at CMU,” (Koblar Jackson, Valeri Petkov, Mary Tecklenburg, Bobby Howell, Brad Fahlman), $695,735, 3 years, January 2007. This project will link together the activities of a group of individually successful researchers to create the Advanced Materials Research Initiative at CMU.  Funded.

2.      Research Excellence Fund, “Teeth vs. Bones: Nano-crystalline Properties of Apatite,” (co-investigator: Marco Fonari), $119,998 2 years, submitted October 2006. Not Funded.

3.      Faculty Insight Team Grant, “An Interdisciplinary Study of Apatite: From Rocks and Bones to Nanomaterials,” $9000, 5/15/2005 – 5/14/2007. (Team members: Mary Tecklenburg, Mona Sirbescu, Marco Fonari and 3 or more students) Supports interdisciplinary discussion and training in collection of natural apatites, preparation of synthetic apatites, analysis, and computation. Funded.

4.      Research Excellence Fund, “Using Raman Microscopy for Spatially Resolved Polymorph Crystallization Kinetics,” (co-investigator: Dale LeCaptain), $98,832, 2 years, submitted October 2002. Not Funded.

5.      FRCE Sabbatical Grant Award, Central Michigan University, “Bone Analysis by Micro-Raman Spectroscopic Imaging,”  $1000, Aug. 2000, 1 year.  Description:  An investigation of the distribution of the mineral components in bone by micro-Raman imaging spectroscopy and DFT calculations of Raman spectra. Funded.

6.      CMU Technology Planning Board, “Upgrades for the Chemistry Department Computer Instruction Laboratory,” (co-author: Ken Magnell) $25,247, April 1999, 1 year. A proposal to replace four Macintosh computers, four Gateway 2000 computers and upgrade four Gateway 2000 computers in the chemistry department computer instruction lab and to purchase licenses for four new software packages. Funded.

7.      Research Excellence Fund, "Effect of Metal Additives on Optical Properties of Ge‑Se‑Te Glasses", (co-investigator: Didarul Islam) $55,470, August 1995, 2 years. A series of Ge‑Se‑Te glasses doped with Zn, Cd, and In will be synthesized.  The optical properties will be measured and correlated with changes in the structure as determined from Raman spectroscopy. Funded.

8.      Research Excellence Fund, "Investigating the Network Structure of Chalcogenide Glassy‑Films" (co-investigators: Didarul Islam, Koblar Jackson) $65,367, May 1993, 2 years.  A set of GeSe2 glasses doped with Cu was synthesized.  The structure of the glasses was deduced by Raman spectroscopy and theoretical calculations.  Changes in the structure were correlated with the optical properties. Funded.

9.      Faculty Research and Creative Endeavors Award, Central Michigan University, "The Heme Structure in Cytochrome c Oxidase using Resonance Raman Spectroscopy", $4,125, March 1992, 1 year.  Resonance Raman spectra of several heme containing proteins and synthetic hemes were compared with that of cytochrome c oxidase. Funded.

 

VII.  Professional Growth Activities

 

A.     Research Leaves

 

1.      Sabbatical Leave, “Bone Analysis by Micro-Raman Spectroscopic Imaging”, (collaborators: Michael Morris, University of Michigan and K. Alan Jackson, Central Michigan University), September 2000 – May 2001.

 

B.      Short Courses and Seminars

 

1.      “Medical Mineralogy and Geochemistry,” Mineralogical Society of America Short Course, Menlo Park, CA, December 9-10, 2006.

2.      “Using Blackboard to Improve Student Learning,”  CMU, May 24-27, 2004.

3.      “The Art and Craft of Teaching,” Lily Conference on College and University Teaching, Traverse City, MI, September 19-21, 2003.

4.      “Conference on Non-Traditional Funding” CMU, November 8, 2002.