SHARMA, Ajit


	Department of Chemistry

Home

Alphabetical

Administration & Staff

Faculty

Emeritus

Visiting Scientists & Postdocs

Ajit Sharma

Ph.D., Wayne State University

Office: Dow 346

Phone: (989) 774 - 3303

Fax: (989) 774 - 3883

E-mail: sharm1a@mail.cmich.edu

Additional Information at: Dr. Sharma's Home Page

Research Program and Goals:

My research interests are in the areas of Biochemistry and Clinical Chemistry. More specifically these include:

    1. Biochemical and clinical aspects of protein aggregation.
    2. Solving applied problems for clinical laboratories.
    3. Development of novel analytical techniques for clinical analysis.

Due to the diverse nature of my research, I collaborate with organic and polymer chemists and with many different clinical professionals (medical technologists, physicians and nurses).

Selected Publications:

1. Sharma, A, Desai A and Ali R, Tomalia, D. Polyacrylamide gel electrophoresis separation and detection of polyamidoamine dendrimers possessing various cores and terminal groups. J Chromatography A, 1081, 238-244 (2005).

2. Sharma A, Rao, M., Miller, R, Desai. Fluorometric assay for detection and quantitation of polyamidoamine dendrimers. Anal. Biochem. 24, 70-75 (2005).

3. Sharma A, Mohanty DK, Desai A and Ali R. A simple polyacrylamide gel electrophoresis procedure for the separation of polyamidoamine dendrimers.Electrophoresis 24, 2733-2739 (2003).

4. Sharma L and Sharma A. Influence of ring substituents on folding-relatedaggregation of bovine carbonic anhydrase. Eur. J. Biochem. 268, 2456 (2001)

5. Sharma L, Baker J, Brooks AM, Sharma A. Study of IgM aggregation in serum of patients with macroglobulinemia. Clin. Chem. Lab. Med. 38, 759-764 (2000).

6. Brandstadt KF, Saam JC, Sharma A. Enzyme-catalyzed direct polyesterification. Polymer Preprints 41, 1857 (2000)

7. Peiris DM, Mohanty DK, Sharma A. Undesirable reaction of aqueous cyclodextrin solutions with polypropylene; Microchemical J. 62, 266-272 (1999)

8. Karuppiah N and Sharma A. Cyclodextrins as protein folding aids, Biochem. Biophy. Res. Comm. 211, 60-66 (1995).

9. Xu Pei-Pei, Troupe CM and Sharma A. Interference by cyclodextrins in protein determination by the bradford method, Microchem. J. 49, 85-90 (1994).

10. Kaufman PB, Kapustka SA and Sharma A. Use of cyclodextrin-cholesterol complex as a primary standard in cholesterol analysis, Microchem. J. 47, 325-329 (1993).